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Y. M. Saif, D.V.M., Ph.D., Diplomat, A.C.V.M., A.C.P.V., Head, Food Animal Health Research Program
Research areas: diseases of poultry and immune response of avian species. Current projects involve infectious bursal disease virus infections and enteric viruses of turkeys. Special emphasis is on studies of pathogenic, antigenic and immunogenic characteristics of infectious bursal disease virus and the role of enteric viurses in diseases of young turkeys. Development of methodologies for study and diagnosis of the infections.
saif.1@osu.edu
David A. Benfield, Ph.D., Professor, FAHRP, Associate Director, OARDC
Research areas: virology, molecular virology, viral pathogenesis, diagnosis of viral infections
Renukaradhya Gourapura, D.V.M., Ph.D., Assistant Professor
Mucosal immunology is increasingly gaining attention as an area of great potential for the development of vaccines and immunotherapy. We are interested in understanding mucosal immune responses in the respiratory and gastrointestinal tract of pigs and other species of food animals following microbial infections. Our main goal is to understand host-pathogen interactions, pathogenesis, microbial immune evasion mechanisms and development of novel mucosal vaccines against infectious diseases. Emphasis is on understanding the role of mucosal innate immune responses mediated through natural killer (NK) cells, gd T cells, NKT cells, dendritic cells and macrophages. Currently, we are involved in elucidation of mucosal immune responses to porcine reproductive and respiratory syndrome (PRRS) virus in the respiratory tract of pigs and development of effective mucosal vaccine to PRRS. Identify potential mucosal candidate adjuvants capable of activating primarily mucosal innate immune cells in the respiratory tract of pigs which in turn activates the adaptive arm of the immune system, and use selected potential adjuvant/s along with specific vaccine antigens to protect against infections/zoonotic diseases of food animals.
gourapura.1@osu.edu
Juliette Hanson, D.V.M., Clinical Veterinarian, Animal Care Manager
hanson.104@osu.edu
Daral J. Jackwood, Ph.D., Professor
Research areas: determining the molecular basis for pathogenicity and immunogenicity of pathogens that infect poultry, including infectious bursal disease virus (IBDV). Recombinant DNA techniques are being used to develop new control and diagnostic procedures for pathogens. The work involves identification of genes coding for virulence factors or immunogenic proteins and cloning and expression of these genes in appropriate systems. Major research interests include molecular epidemiology and improving molecular diagnostics and control measures used for an immunosuppressive viral disease in poultry.
jackwood.2@osu.edu
Mahesh Khatri, Ph.D., Research Scientist
Research areas: mucosal immununology of porcine reproductive and respiratory syndrome (PRRS) virus, identification of potential mucosal candidate adjuvants and studying protective mucosal immune response to infectious diseases.
Chang-Won Lee, D.V.M., Ph.D., Assistant Professor
Research areas: microbiology, molecular virology, avian influenza
lee.2854@osu.edu
Jeffrey T. LeJeune, D.V.M., Ph.D., Associate Professor
Research areas: preharvest control of human foodborne pathogens and antimicrobial-resistant bacteria in the animal host and the environment. Projects integrate epidemiological principles with traditional and molecular biological approaches to elucidate the effects of the animal host, environment, and pathogen on the epidemiology of important bacterial foodborne diseases. Other areas of interest include other bacterial zoonoses and infectious diseases of farmed fanfish.
lejeune.3@osu.edu
Gireesh Rajashekara, Ph.D., Assistant Professor
Research areas: Microbiology, bacteriology
Linda J. Saif, Ph.D., Distinguished University Professor, Member of National Academy of Sciences
Research areas: diagnosis, molecular characterization, pathogenesis, vaccine design, and immunity to enteric and respiratory viruses of swine and cattle. Emphasis is also on studies of disease pathogenesis and immunity using animal models of human enteric viral infections (rotavirus, noroviruses) and of respiratory viruses (coronaviruses). Current emphasis is on passive immunity and mucosal B- and T-cell and cytokine immune responses to enteric viruses; design of genetically engineered vaccines; and studies of mucosal adjuvants, immunomodulators, and delivery systems.
saif.2@osu.edu
Qiuhong Wang, Ph.D., Adjunct Assistant Professor, Research Scientist
Research areas: virology, Calicivirus
wang.655@osu.edu |
